Ribbon structure of the BRCA2 protein. Mutations in the BRCA2 gene are linked to increased risk of breast cancer. New work from UC Davis shows how individual BRCA2 proteins work to repair damaged DNA, ...

Researchers found that losing a second protein, FIGNL1, allows cancer cells missing BRCA2 to restore DNA repair by reloading RAD51 onto broken DNA strands. Normally, BRCA2 helps place RAD51 at DNA ...

Vickie Doogan got her dog Dolly during breast cancer recovery. Years later, Dolly was diagnosed with the same disease and also had a mastectomy.

The breast cancer type 2 susceptibility (BRCA2) protein, which is frequently mutated in hereditary breast cancer, is involved in the repair of DNA double-strand breaks by homologous recombination ...

Researchers from the U.K. and the U.S. have called for immediate action to recommend screening for prostate cancer for men with BRCA2 mutations over the age of 40 after presenting the results of a new ...

Add Yahoo as a preferred source to see more of our stories on Google. I started getting mammograms at the age of 30. I didn’t know a lot about my family history because I was adopted at birth, but I ...

The initials BRCA2 may be best known for a gene associated with many cases of breast cancer, and the protein encoded by the BRCA2 gene is critical to repairing breaks in DNA. The breakdown of this ...

The FDA approved niraparib and abiraterone acetate (Akeega) in combination with prednisone for treating BRCA2-mutated metastatic castration-sensitive prostate cancer (mCSPC), the agency announced on ...

After a breast-cancer diagnosis and a separate scare, my mom tested for the BRCA2 gene mutation. Knowing it could be hereditary, I decided to get tested at 23 to see if I also carried the mutation. My ...

More than 14,000 women learn they have ovarian cancer each year, and despite recent advances in the treatment of the disease, the prognosis remains discouraging. For newly diagnosed patients, fewer ...

new study shows exactly how the gene BRCA2, linked to susceptibility to breast and ovarian cancer, functions to repair damaged DNA. By studying BRCA2 at the level of single molecules, researchers at ...