New research reveals that aging immune cells can become locked in a self-sustaining inflammatory state, worsening the body’s ability to respond to severe infections.

The progress in understanding the pathophysiology of hidradenitis suppurativa appears to be leading to treatment strategies ...

Dendritic cells (DCs) are among the first immune sentinels to detect viruses, bacteria, or other challenges. These specialized messengers alert T cells while orchestrating either a measured calm or a ...

A University of Kentucky Markey Cancer Center study reveals how prostate cancer cells adapt their metabolism to thrive in ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

The field of sepsis research has advanced significantly in recent years, particularly regarding the interplay between immune responses and multiple forms of ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

SereNeuro Therapeutics revealed promising results for SN101, a first-in-class iPSC-derived therapy designed to treat chronic osteoarthritis pain while protecting joint tissue. Instead of blocking pain ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

Seals give birth only when conditions are right. After mating, a female seal can delay implantation of the embryo in the ...