BIRMINGHAM, Ala. – Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages — the white blood cells that defend the body by killing microbes, ...

Triggering receptors expressed on myeloid cells (TREMs) are a cell surface receptor family found on granulocytes, monocytes, macrophages, and dendritic cells—as well as other myeloid cells in general.

New research combines two powerful imaging techniques to study the complete structure of a common aGPCR, including how its long and complex extracellular region interacts with the transmembrane region ...

A new review links three forces shaping osteoarthritis: mechanical stress, integrin signaling, and integrin endocytosis. The authors argue that integrin trafficking can reprogram where and how long ...

Veronica Paulus is a former STAT intern supported by the Harvard University Institute of Politics. One in five individuals who receive a kidney transplant experience a rejection episode within a year.

Recently these monocyte-derived alveolar macrophages, or Mo-AMs, were identified as key drivers of lung fibrosis disease progression. However, the mechanisms of their pro-fibrotic behavior and ...