Article reviewed by Govind Kaigala, PhD at the University of British Columbia. Stay up to date on the latest science with Brush Up Summaries. In situ hybridization (ISH) is a molecular technique that ...

DNA can signal the presence of or predisposition to a slew of diseases, including cancer. The ability to flag down these clues, known as biomarkers, allows medical professionals to make critical early ...

Probes are short, single-stranded chains of nucleic acid that seek out and latch themselves to a complementary sequence of nucleic acids, often buried anonymously in a much larger section of DNA/RNA.

Part of the device is coated with single strands of DNA. When these "probes" encounter DNA biomarkers that have a corresponding, or complementary, genetic sequence, the two strands bind, sending a ...

Pipettes? Check. Centrifuges? Check. Microplates? Check. Gloves? Check. Salmon sperm DNA? Check. Wait what? There are a ...

Characterized by the formation of a stem-loop (hairpin) structure, Molecular Beacon Probes from LGC Biosearch Technologies are dual-labeled probes in which the reporter and quencher come into close ...