As one of the inventors of next-generation DNA sequencing, Sir Shankar Balasubramanian could claim to be responsible for a revolution in the life sciences. Balasubramanian and chemist David Klenerman, ...

Mutations are changes in the molecular 'letters' that make up the DNA code, the blueprint for all living cells. Some of these changes can have little effect, but others can lead to diseases, including ...

Proteins are like Spider-Man in the multiverse. The underlying story is the same: each building block of a protein is based on a three-letter DNA code. However, change one letter, and the same protein ...