New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

Researchers at the University of Würzburg, led by Caroline Kisker in cooperation with Claudia Höbartner, discovered how the protein XPD detects a severe DNA damage and controls its repair. The XPD ...

Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever cells ...

A new fluorescent sensor is giving scientists an unprecedented view of how cells respond to DNA damage, capturing the repair process as it unfolds in real time. The tool, developed at Utrecht ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...

The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide excision repair, or NER. NER’s protein components can change shape to ...

The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...

In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises unfold in real time. Inside every cell, DNA breaks, repairs, and sometimes ...

A team of scientists led by the National Cancer Center Singapore (NCCS) and Duke-NUS Medical School (Duke-NUS) has found a new approach for treating some of the world's most aggressive cancers ...

New research from the Kind Group at the Hubrecht Institute sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human ...