A University of Saskatchewan (USask) research team's discovery of the additional health benefits of an appetite-suppressing protein has doubled the potential for scientists to find new avenues for ...

New research has identified hundreds of proteins that might contribute to the onset of common, chronic metabolic diseases such as type 2 diabetes, and consequently pathways to potential treatments.

Thioredoxin-interacting protein (TXNIP) is increasingly recognised as a central regulator in cellular redox homeostasis. By binding to thioredoxin, TXNIP modulates the cell’s antioxidant defences, and ...

Discovery of an appetite-suppressing protein has doubled the potential for new avenues for treating obesity and metabolic disorders in animals and people. A University of Saskatchewan (USask) research ...

Pro-inflammatory cytokines (TNF-α, IL-6, and IL-1β) are produced in large quantities locally in the joints and subsequently enter the bloodstream. TNF-α and IL-6 may promote LDL metabolism by ...

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide. This prevalent condition is also linked to other metabolic disorders, including type 2 ...

Metabolism is the essential bodily process of creating energy from food. Food consists of nutrients that the chemicals of the digestive system break down into sugars and acids for fuel. Metabolic ...

An innovative gene-editing strategy could establish a new way for the body to manufacture therapeutic proteins—including ...

Magnesium is an important cofactor for numerous enzymes. All ATPase reactions require Mg 2+ –ATP, including those involved in RNA and DNA biologic functions. It opposes calcium actions and acts as a ...

Forbes contributors publish independent expert analyses and insights. Harvard Medical School Professor, Metabolic Health Innovator Metabolism is often reduced to a simple equation of calories in ...