Scientists studying a COVID-19 coronavirus enzyme at temperatures ranging from frosty to human-body warm discovered subtle structural shifts that offer clues about how the enzyme works. The findings ...

The structure of a key enzyme involved in protein production is revealed by cryo-electron microscopy (cryo-EM). Using cryo-EM, researchers at Goethe University (Frankfurt, Germany) shed light on ...

Structural models of PLD3 and PLD4, enzymes that degrade nucleic acids in the cytoplasm. The enzymes' active (or binding) sites are indicated with black arrows. LA JOLLA, CA—When nucleic acids like ...

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA.

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system. Enzymes usually clear these nucleic acids before they cause an issue, but when these ...

Scientists discovered hundreds of energy-making enzymes secretly working on human DNA—revealing a hidden “mini-metabolism” ...