When the liver is injured - for example, due to bile accumulation - immune cells become activated. In mouse experiments, the ...

A study shows mitochondrial electron flow keeps dendritic cells primed, regulating gene activity and T-cell activation. The ...

The research group of Prof. Sanjiv Luther at the Department of Immunobiology of the University of Lausanne has discovered ...

The immune system has evolved to mount immune responses against foreign pathogens and to remain silent against self-antigens. A balance between immunity and tolerance is required as any disturbance ...

EPFL researchers have successfully engineered cells of the immune system to more effectively recognize cancer cells. The work, covered in two papers, turns the previously lab-based method into a ...

Potential autoimmune diseases therapies that target dendritic cells aim to either inhibit immunogenic dendritic cell functions or support their tolerogenic potential (Figure 2). Most strategies ...

Dendritic cells (DCs) are among the first immune sentinels to detect viruses, bacteria, or other challenges. These specialized messengers alert T cells while orchestrating either a measured calm or a ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

Scientists at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the Institute for Research in ...