Delve into the field of PARP inhibitors, a class that has gained traction in ovarian, breast, and prostate cancers.

Scientists now recognize that spontaneous DNA errors, which we acquire in early development all the way until our last breath ...

Serif Biomedicines has emerged from stealth with $50 million in start-up funding. The new firm is developing what it calls ...

The human immune system is finely tuned to detect and destroy viral threats. But this same defense system can misfire. When ...

A protein long studied for its role in amyotrophic lateral sclerosis and frontotemporal dementia now appears to serve a second, equally critical function, safeguarding the integrity of human DNA.

A protein that helps embryonic stem cells (ESCs) retain their identity also promotes DNA repair, according to a study in The Journal of Cell Biology. The findings raise the possibility that the ...

Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.