When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory response. It’s just as important to be able to resolve that inflammation and ...

It is well known that chronic inflammation can increase a person’s cancer risk, but the underlying mechanisms remain unknown. Now, a new study reveals, in a mouse model of colitis, gut tissues may ...

Researchers at Brigham and Women’s Hospital have identified a new class of small molecules that selectively shut down ...

In IAV-infected wild-type AECII, ELOVL5 promoted inflammation resolution and cell proliferation through both regulating lipid metabolism (promoting PUFAs generation while decreasing eicosanoid levels) ...

The field of extracellular vesicle (EV) biology has rapidly expanded, revealing that these membrane-bound nanoparticles are crucial mediators of ...

The medical community increasingly recognizes chronic inflammation as a fundamental driver behind numerous health conditions, from obvious manifestations like rheumatoid arthritis and inflammatory ...

Researchers have uncovered epigenetic signatures behind persistent cellular memories of inflammation, which can drive chronic ...

TAM receptors are key in immune regulation and inflammation resolution, with Axl and MerTK offering protective benefits in RA, while Tyro3 may worsen inflammation. Soluble TAM receptors (sTAMs) could ...

Our proprietary PAIR technology is designed to address inflammation further upstream, reducing the cascade of damage before it begins. By targeting inflammation at its source through dual mechanisms ...