A specific regulatory protein significantly influences the development of tumor-inducing blood vessels in the bone marrow of blood cancer patients. Using a series of different experiments, the team ...
Altered expression of the KAI1 metastasis suppressor gene (Dong et al., 1995) in a wide range of human tumours is now well established (reviewed in Jackson and Marreiros, 2004). However, the ...
The transcription factor PU.1 (encoded by Sfpi1) is indispensable for myelomonocytic differentiation during normal hematopoiesis 1. Several reports suggest that reduced function of PU.1 might also ...
A research team led by physicians of the Karl Landsteiner University of Health Sciences in Krems (KL Krems) uncovers a pivotal role for a regulator protein in tumour bone marrow angiogenesis. Krems, ...
Researchers learn how a key transcription factor helps regulate the immune system and could be critical to understanding autoimmune disease and cancer immunosuppression. Our immune systems defend our ...