An expert from CN Bio explores considerations when choosing an in vitro liver model . As the major drug metabolising organ, ...

A new mouse model mimicking the liver symptoms of myotonic dystrophy type 1 -- the most prevalent form of adult-onset muscular dystrophy -- provides insight into why patients develop fatty liver ...

Liver cancer is one of the world's deadliest cancers, and most cases are linked to chronic viral hepatitis. Yet scientists have lacked an animal model that faithfully recapitulates how the disease ...

Periportal assembloid, with the three component cell types visualized: cholangiocytes in pink, portal fibroblasts in green, and hepatocyte nuclei in blue; all cell borders are visualized in white. New ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

The paper S. Hoehme et al., “Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration,” PNAS, 107:10371-76, 2010. Free ...

Bottom line: A machine learning model that analyzes patient demographics, electronic health record data, and routine blood test results predicted a patient's risk of hepatocellular carcinoma (HCC), ...

Liver scarring can pave the way to cancer down the line. A new blood test in development might help doctors spot it.