A joint study revealing a new mechanism on DNA Replication Initiation, led by The University of Hong Kong (HKU), The Hong Kong University of Science and Technology (HKUST), and other institutions, has ...
The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...