Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Patients with chronic back pain reported heightened unpleasantness of auditory stimuli and mechanical pressure.

Many horse owners think the existence of the prefrontal cortex is a major controversy in equine science. It’s not. It’s just an area that’s riddled with misinformation. Curiously, most people—horsey ...

The brain may organize emotions like locations on a map, revealing a hidden system that helps people interpret changing feelings.

Increasing physical fitness leads to a larger release of BDNF and better prefrontal cortex activity after a single session of exercise.