Pyrosequencing can be used to detect DNA and RNA from almost any source, and has applications in bacteria resistance screening, drug development, epigenetics, and many other fields. If no light is ...

Figure 1: Enzymatic cascade of the pyrosequencing reaction in the example of a bisulfite-treated template sequence, including a CpG position that is methylated on approximately 50% of all molecules.

Recent estimates of the number of species in a gram of soil have garnered much attention. Such estimates are of particular interest as soil is considered to harbor the most diverse populations of ...

Phase Ib clinical trial of OKN-007 in recurrent malignant glioma. This is an ASCO Meeting Abstract from the 2020 ASCO Annual Meeting I. This abstract does not include a full text component.

The sequencing of DNA molecules started with the development of chemical cleavage method of Maxam-Gilbert during 1970s followed by di-deoxy chain termination method. However, the whole genome ...

Risk-adjusted survival for melanoma brain metastases in the era of checkpoint blockade immunotherapies: Results from a national cohort. This is an ASCO Meeting Abstract from the 2018 ASCO Annual ...

Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter. Pal Nyren’s Eureka moment came in 1986 when he was cycling home from Cambridge university. “It is often when ...

DNA methylation is a form of epigenetics in which gene expression is encouraged or inhibited by the addition of a methyl group on cytosines. It is highly implicated in development, cell ...