A signaling pathway best known for shaping the brain before birth also helps govern how adults learn, adapt, and persist in ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Researchers discovered that suppressing BMP signaling in astrocytes reduces seizures and restores brain balance in Fragile X syndrome models.

Cells long thought to play a secondary role in brain function build their own far-reaching connections, according to a new ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

Fragile X syndrome (FXS) is an inherited genetic developmental condition that strongly impacts brain development. Despite the ...

Glioblastoma remains a highly challenging malignancy with a pronounced tendency for recurrence. The hypoxic microenvironment ...

BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...

A research team has uncovered how key polyphenols from dandelion help suppress inflammation by regulating the AGE–RAGE signaling pathway, a biological route strongly linked to chronic inflammatory ...

The simplest explanations are often the most appealing, yet they are also often the most incomplete. For a long time, it ...