A signaling pathway best known for shaping the brain before birth also helps govern how adults learn, adapt, and persist in ...

Researchers discovered that suppressing BMP signaling in astrocytes reduces seizures and restores brain balance in Fragile X syndrome models.

Fragile X syndrome (FXS) is an inherited genetic developmental condition that strongly impacts brain development. Despite the ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

Serotonin from antidepressants may amplify tinnitus, offering insight into why ear ringing can worsen during treatment.

Glioblastoma remains a highly challenging malignancy with a pronounced tendency for recurrence. The hypoxic microenvironment ...

BACKGROUND: Genetic variants in components or regulators of the RAS-MAPK signaling pathway are causative for severe and early-onset hypertrophic cardiomyopathy (HCM) in patients with Noonan syndrome ...

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a ...

A research team has uncovered how key polyphenols from dandelion help suppress inflammation by regulating the AGE–RAGE signaling pathway, a biological route strongly linked to chronic inflammatory ...