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Replying to @postcardplaces #endocrinologist #thyroid #TallCellVariant What is Tall Cell Variant PTC? It is a histologic subtype of papillary thyroid carcinoma. Characterized by tall, columnar cells that are at least twice as tall as they are wide. These cells have abundant eosinophilic (pink) cytoplasm. The nuclei show typical PTC features: nuclear grooves, clearing (Orphan Annie eye nuclei), and nuclear overlapping. Clinical Features Typically occurs in older patients (usually >50 years). Gene
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